The Greenberg Conference Center provides executive meeting facilities for Yale University's Office of International Affairs, which holds seminars and conferences that attract distinguished guests from all over the world. The building is linked by a glazed arcade to the historic Betts House (Henry Austin and David R. Brown, 1868, restored 2002) and is sited in keeping with the historic pattern of Prospect Street, where large residences—many now converted to institutional uses—are set back from the sidewalks to occupy the high point of their lots. The new building rotates eastward away from the street to allow Betts House to maintain its visual prominence; the glazed connector defines a raised landscaped courtyard. The new building carries forward the earlier building's palette of mauve stucco walls scored to simulate dressed stone over a brown ashlar masonry base. Columns, arches, and treillage panels on the porches and the connector complement the detailing of the Betts House porch.
The sloping site allows part of the lower level of the Greenberg Center to be buried into the hillside. The Greenberg Center accommodates an amphitheater and offices on the lower level and a classroom and reception rooms on the upper level. The generously proportioned lobby can host receptions for up to eighty people. The wood-paneled walls and arcuated wood ceiling ribs and beamwork of the dining room evoke the dining halls of James Gamble Rogers's Yale residential colleges. A large Serlian bay window orients the room to an east-west axis and arched French doors leading to the south-facing terrace offer sweeping views across the grounds. To support the Center's diverse guests, the major gathering spaces are served by language interpretation booths.